MMPs
MMPs (Matrix metalloproteinases) are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the These enzymes are capable of degrading all kinds of extracellular matrix proteins, but also can process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands (such as the FAS ligand), and chemokine/cytokine inactivation.[3] MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
-
UK 370106是高选择性MMP-3，MMP-12抑制剂。
More
-
UK 383367是活性选择性BMP-1 (PCP)抑制剂。
More
-
SD 2590 hydrochloride是活性的 MMP 抑制剂。
More
-
Ro 32-3555是活性collagenase选择性的MMP抑制剂。
More
-
PTIQ是活性MMP-3 激活、表达的抑制剂， 具有神经保护活性。。
More
